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nucleoporin 214

Summary

Gene Symbol

NUP214

Organism

Homo sapiens (human)

External Links

NCBI Gene

8021

PubChem

8021

Alliance of Genome Resources

HGNC:8064

JoGo

NUP214

TogoVar

NUP214

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Chromosomal rearrangement
Coiled coil
Disease variant
Glycoprotein
Host-virus interaction
Isopeptide bond
Nuclear pore complex
Phosphoprotein
Proteomics identification
Proto-oncogene
Reference proteome
Repeat
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B7ZAV2
P35658	214 kDa nucleoporin Nucleoporin Nup214 Protein CAN

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
RNA export from nucleus	IBA
mRNA export from nucleus	IMP	10557333
protein import into nucleus	IBA
protein export from nucleus	IMP	12191473
nucleocytoplasmic transport	NAS	27016207

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

mRNA export from nucleus

protein export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

establishment of protein localization to organelle [inference]

protein import into nucleus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

mRNA export from nucleus

protein export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

mRNA export from nucleus

protein export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

mRNA export from nucleus

protein export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

regulation of cellular process [inference]

regulation of cell cycle

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nuclear envelope	IDA	24315095
nuclear pore	NAS	24315095
nuclear pore	IBA
nucleoplasm	TAS
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear pore

cellular anatomical entity [inference]

envelope [inference]

organelle envelope [inference]

nuclear envelope

cytoplasmic side of nuclear pore

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nuclear export signal receptor activity	IDA	10358091
protein binding	IPI	11545741 11777942 14766228 19208808 19219046 30021884 30543681 33961781 35271311
nuclear localization sequence binding	IBA
structural constituent of nuclear pore	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

signal sequence binding [inference]

nuclear localization sequence binding

molecular carrier activity [inference]

nucleocytoplasmic carrier activity [inference]

nuclear export signal receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Nuclear pore complex protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
RNA export from nucleus
nuclear localization sequence binding
protein import into nucleus

Displaying **all 2** entries
InterPro
Nuclear pore complex protein
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:9119	acute myeloid leukemia	Alliance of Genome Resources
DOID:936	brain disease	Alliance of Genome Resources
DOID:9952	acute lymphoblastic leukemia	Alliance of Genome Resources