ADAM metallopeptidase domain 12

Summary
Gene Symbol
  • ADAM12
Organism
Homo sapiens (human)
NCBI Gene
8038
KEGG Gene ID
PubChem
8038
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Cell adhesion
  • Cell membrane
  • Cleavage on pair of basic residues
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Integrin
  • Metal-binding
  • Metalloprotease
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • SH3-binding
  • Secreted
  • Signal
  • Transmembrane
  • Transmembrane helix
  • Zinc
  • Zymogen
Proteins
Displaying all 4 entries
UniProt Protein Name
A8K6G4
Q5JRP2
O43184
  • Meltrin-alpha
A0ACM8QT74
Gene Ontology (GO)
Displaying entries 1 - 5 of 6 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
cell adhesion
integrin-mediated signaling pathway
myoblast fusion
GO Hierarchy
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:8398 osteoarthritis
Ortholog
Displaying all 2 entries
Species Gene ID Alliance of Genome Resources
11489 MGI:105378
181489 WB:WBGene00000074

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026