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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
calreticulin
Summary
- Gene Symbol
-
- CALR
- Aliases
-
- CRT
- FLJ26680
- RO
- SSA
- Sicca syndrome antigen A (autoantigen Ro; calreticulin)
- autoantigen Ro
- cC1qR
- calregulin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Calcium
- Chaperone
- Cytoplasm
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Hydroxylation
- Lectin
- Lysosome
- Metal-binding
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Signal
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to estradiol | ||
| peptide antigen assembly with MHC class I protein complex |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell motility [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| lumenal side of endoplasmic reticulum membrane |
|
|
| endoplasmic reticulum quality control compartment | ||
| endoplasmic reticulum membrane | ||
| cell surface |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding |
|
|
| integrin binding | ||
| zinc ion binding |
|
|
| nuclear androgen receptor binding | ||
| protein folding chaperone |
|
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3069 | malignant astrocytoma | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3074 | giant cell glioblastoma | |
| DOID:3078 | anaplastic astrocytoma | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3119 | gastrointestinal system cancer | |
| DOID:3121 | gallbladder cancer | |
| DOID:3127 | proctitis | |
| DOID:3172 | papillary adenoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000505 | Visual impairment |
| HP:0000952 | Jaundice |
| HP:0000967 | Petechiae |
| HP:0000978 | Bruising susceptibility |
| HP:0000979 | Purpura |
| HP:0000980 | Pallor |
| HP:0001028 | Hemangioma |
| HP:0001082 | Cholecystitis |
| HP:0001394 | Cirrhosis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:824 |
|
| OMIM:254450 |
|
| ORPHA:3318 |
|
| OMIM:187950 |
|
| ORPHA:131 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 178997 | WB:WBGene00000802 | ||
| 41166 | FB:FBgn0005585 | ||
| 325317 | ZFIN:ZDB-GENE-030131-4042 | DANRE43330 | |
| 108265943 | ICTPU29931 | ||
| 113581087 | ELEEL27705 | ||
| 106599148 | SALSA112940 | ||
| 115156816 | SALTR62730 | ||
| 115158393 | SALTR109455 | ||
| 115169886 | SALTR41851 | ||
| 115192495 | SALTR30222 |
