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MIRAGE
transforming growth factor, beta receptor 2
Summary
- Gene Symbol
-
- Tgfbr2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| D0VED2 |
|
| A0A8L2QK15 |
|
| P38438 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| branching involved in blood vessel morphogenesis | ||
| branching involved in blood vessel morphogenesis | ||
| vasculogenesis | ||
| vasculogenesis | ||
| vasculogenesis |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of tolerance induction [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| plasma membrane | ||
| plasma membrane | ||
| caveola | ||
| caveola |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane receptor protein serine/threonine kinase activity | ||
| transforming growth factor beta receptor activity | ||
| transforming growth factor beta receptor activity | ||
| transforming growth factor beta receptor activity, type I | ||
| transforming growth factor beta receptor activity, type II |
GO Hierarchy
- molecular adaptor activity
molecular function
catalytic activity [inference]
binding [inference]
molecular transducer activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- TGF-beta receptor type-2
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| SMAD binding |
| activin binding |
| activin receptor activity |
| anatomical structure morphogenesis |
| cell differentiation |
| kinase activity |
| metal ion binding |
| nucleotide binding |
| phosphorylation |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2920 | membranoproliferative glomerulonephritis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101146131 | GORGO28083 | ||
| 101327734 | TURTR08881 | ||
| 101567492 | OCTDE11229 | ||
| 101607560 | JACJA13678 | ||
| 101811048 | FICAL00628 | ||
| 101871197 | MELUD01586 | ||
| 101936050 | CHRPI33234 | ||
| 101957948 | ICTTR03711 | ||
| 102022415 | CHILA08917 | ||
| 102293387 | HAPBU12887 |
