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Repository for lectin-assisted multimodality data

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Glycan Converters

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Guidelines

MIRAGE

symplekin scaffold protein

Summary

Gene Symbol

SYMPK

Organism

Homo sapiens (human)

External Links

NCBI Gene

8189

PubChem

8189

Alliance of Genome Resources

HGNC:22935

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Cytoskeleton
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Tight junction
Ubl conjugation
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q92797

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
negative regulation of protein binding	IMP	29158257
mRNA processing	IEA
cell adhesion	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular process [inference]

cell adhesion

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

biological regulation [inference]

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of protein binding

regulation of binding [inference]

regulation of protein binding [inference]

negative regulation of protein binding

negative regulation of binding [inference]

negative regulation of protein binding

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
mRNA cleavage and polyadenylation specificity factor complex	IBA
cytoplasm	IDA	8769423
plasma membrane	IDA
nucleoplasm	IDA TAS	8769423
nuclear body	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex [inference]

mRNA cleavage and polyadenylation specificity factor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

nuclear body

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

ribonucleoprotein granule [inference]

nuclear stress granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

ribonucleoprotein granule [inference]

nuclear stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear stress granule

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	14707147 18288197 18688255 20861839 26496610 32814053 33961781 34819669 35177536

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **71 - 75** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Sparus aurata	115587826		SPAAU27860
Chelonoidis abingdonii	116835265		CHEAB05882
Rhinolophus ferrumequinum	117034552		RHIFE00802
Panthera leo	122207812		PANLE30290
Ursus americanus	123778728		URSAM20229

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025