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ubiquitin specific peptidase 9 Y-linked

Summary

Gene Symbol

USP9Y

Organism

Homo sapiens (human)

External Links

NCBI Gene

8287

PubChem

8287

Alliance of Genome Resources

HGNC:12633

Annotation

Keyword

Alternative splicing
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Thiol protease
Ubl conjugation pathway
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
O00507	Deubiquitinating enzyme FAF-Y Fat facets protein-related, Y-linked Ubiquitin thioesterase FAF-Y Ubiquitin-specific protease 9, Y chromosome Ubiquitin-specific-processing protease FAF-Y

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
proteolysis	IEA
transforming growth factor beta receptor signaling pathway	ISS
spermatogenesis	TAS	9384609
cell migration	IBA
protein deubiquitination	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

cell motility [inference]

cell migration

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

regulation of biological quality [inference]

regulation of protein stability

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IBA
cytoplasm	ISS
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cysteine-type deubiquitinase activity	IDA	12895410
cysteine-type deubiquitinase activity	IBA
cysteine-type peptidase activity	TAS	8922996
metal ion binding	IEA
co-SMAD binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

cysteine-type peptidase activity

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

cysteine-type peptidase activity

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

binding [inference]

protein binding [inference]

SMAD binding [inference]

co-SMAD binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070187	Y-linked spermatogenic failure 2	Alliance of Genome Resources

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	8239	ZFIN:ZDB-GENE-061019-1
Danio rerio	8287	ZFIN:ZDB-GENE-061019-1
Danio rerio	22284	ZFIN:ZDB-GENE-061019-1
Caenorhabditis elegans	23358	WB:WBGene00011980
Danio rerio	43749	ZFIN:ZDB-GENE-061019-1
Caenorhabditis elegans	329908	WB:WBGene00011980
Macaca mulatta	100270703		MACMU48715
Papio anubis	116272358		PAPAN43916

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Acknowledgements