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cyclin-dependent kinase inhibitor 1B
Summary
- Gene Symbol
-
- Cdkn1b
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cyclin-dependent protein serine/threonine kinase activity | ||
| G1/S transition of mitotic cell cycle | ||
| G1/S transition of mitotic cell cycle | ||
| response to hypoxia | ||
| placenta development |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
negative regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
negative regulation of phosphorylation
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
negative regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
negative regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
negative regulation of phosphorylation
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
negative regulation of phosphate metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle
regulation of molecular function [inference]
negative regulation of molecular function [inference]
positive regulation of molecular function [inference]
regulation of catalytic activity [inference]
positive regulation of catalytic activity [inference]
negative regulation of catalytic activity [inference]
regulation of transferase activity [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleus | ||
| nucleoplasm | ||
| nucleoplasm | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase inhibitor activity | ||
| cyclin-dependent protein serine/threonine kinase inhibitor activity | ||
| cyclin-dependent protein serine/threonine kinase inhibitor activity | ||
| protein binding | ||
| protein kinase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- CYCLIN-DEPENDENT KINASE INHIBITOR
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cyclin-dependent protein serine/threonine kinase inhibitor activity |
| protein kinase inhibitor activity |
| InterPro |
|---|
| Cyclin-dependent kinase inhibitor domain superfamily |
| Cyclin-dependent kinase inhibitor domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050771 | pheochromocytoma | |
| DOID:0050773 | paraganglioma | |
| DOID:3125 | multiple endocrine neoplasia | |
| DOID:3829 | pituitary adenoma | |
| DOID:5223 | infertility | |
| DOID:5844 | myocardial infarction | |
| DOID:83 | cataract |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1027 | Xenbase:XB-GENE-1032978 | HUMAN11304 | |
| 12576 | MOUSE49595 | ||
| 83571 | Xenbase:XB-GENE-1032978 | ||
| 368329 | DANRE27291 | ||
| 397584 | PIGXX26137 | ||
| 403429 | CANLF11045 | ||
| 466947 | PANTR05231 | ||
| 493958 | FELCA15278 | ||
| 512613 | BOVIN30212 | ||
| 697188 | MACMU04159 |
