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Guidelines
MIRAGE
vascular endothelial growth factor A
Summary
- Gene Symbol
-
- Vegfa
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Angiogenesis
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Heparin-binding
- Mitogen
- Reference proteome
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| vasculature development | ||
| lymphangiogenesis | ||
| blood vessel remodeling | ||
| sprouting angiogenesis | ||
| sprouting angiogenesis |
GO Hierarchy
- regulation of nitric oxide mediated signal transduction
- positive regulation of cell division
- regulation of nitric oxide mediated signal transduction
- regulation of nitric oxide mediated signal transduction
- positive regulation of cell division
biological process
metabolic process [inference]
cellular process [inference]
signal transduction
cellular response to stimulus [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction
regulation of localization [inference]
regulation of growth
regulation of locomotion [inference]
positive regulation of locomotion [inference]
regulation of cell motility [inference]
regulation of cell migration [inference]
positive regulation of cell motility [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction
regulation of developmental process [inference]
regulation of anatomical structure morphogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell population proliferation [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of cell migration [inference]
positive regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of epithelial cell migration [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| basement membrane | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibronectin binding | ||
| fibronectin binding | ||
| cytokine activity | ||
| cytokine activity | ||
| platelet-derived growth factor receptor binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Vascular endothelial growth factor A
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Cystine-knot cytokine |
| PDGF/VEGF domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050852 | limb ischemia | |
| DOID:11396 | pulmonary edema | |
| DOID:13207 | proliferative diabetic retinopathy | |
| DOID:1686 | glaucoma | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:4724 | brain edema | |
| DOID:5425 | ovarian hyperstimulation syndrome | |
| DOID:5844 | myocardial infarction |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7422 | Xenbase:XB-GENE-485744 | HUMAN84993 | |
| 22339 | Xenbase:XB-GENE-485744 | ||
| 30682 | Xenbase:XB-GENE-485744 | ||
| 83785 | Xenbase:XB-GENE-485744 | ||
| 281572 | BOVIN18562 | ||
| 493845 | FELCA12631 | ||
| 574209 | MACMU34310 | ||
| 100713483 | CAVPO08580 | ||
| 100860957 | CAPHI15644 | ||
| 101951073 | CHRPI34010 |
