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solute carrier family 25 member 11

Summary

Gene Symbol

SLC25A11

Organism

Homo sapiens (human)

External Links

NCBI Gene

8402

PubChem

8402

Alliance of Genome Resources

HGNC:10981

Annotation

Keyword

Acetylation
Alternative splicing
Antiport
Direct protein sequencing
Disease variant
Lipid transport
Mitochondrion inner membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q02978	Solute carrier family 25 member 11
Q6IBH0	Solute carrier family 25 member 11

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
alpha-ketoglutarate transport	IEA
phosphate ion transmembrane transport
malate-aspartate shuttle	IMP	37647199
succinate transmembrane transport
malate transmembrane transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

localization [inference]

establishment of localization [inference]

transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

inorganic anion transport [inference]

phosphate ion transport [inference]

phosphate ion transmembrane transport

sulfate transport

sulfate transmembrane transport

thiosulfate transport

inorganic anion transmembrane transport [inference]

transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

organic substance transport [inference]

lipid transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

oxaloacetate transport

malate transport [inference]

malate transmembrane transport

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

oxaloacetate transport

malate transport [inference]

malate transmembrane transport

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

nitrogen compound transport [inference]

sulfate transport

sulfate transmembrane transport

thiosulfate transport

sulfur compound transport [inference]

sulfate transport

sulfate transmembrane transport

thiosulfate transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	HDA	21630459
mitochondrion	HTP	34800366
mitochondrion	HDA	20833797
mitochondrial inner membrane	TAS
plasma membrane	TAS	1457818

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
protein binding	IPI	32814053 37009826
sulfate transmembrane transporter activity
thiosulfate transmembrane transporter activity
oxaloacetate transmembrane transporter activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

alpha-ketoglutarate transmembrane transporter activity [inference]

oxoglutarate:malate antiporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

alpha-ketoglutarate transmembrane transporter activity [inference]

oxoglutarate:malate antiporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

sulfate transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

oxoglutarate:malate antiporter activity

sulfur compound transmembrane transporter activity [inference]

salt transmembrane transporter activity [inference]

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mitochondrial uncoupling protein

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Mitochondrial carrier domain superfamily
Mitochondrial carrier protein
Mitochondrial substrate/solute carrier

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050773	paraganglioma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	8402	Xenbase:XB-GENE-5760490
Rattus norvegicus	64201	Xenbase:XB-GENE-979673	RATNO00161
Mus musculus	67863	Xenbase:XB-GENE-979673	MOUSE06672
Bos taurus	282523		BOVIN12664
Sus scrofa	397390		PIGXX03229
Danio rerio	415189		DANRE35826
Pan troglodytes	468167		PANTR13318
Canis lupus familiaris	479470		CANLF15404
Macaca mulatta	710569		MACMU14499
Monodelphis domestica	100017448		MONDO10763