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Guidelines

MIRAGE

alcohol dehydrogenase ADH5

Summary

Gene Symbol

ADH5

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852442

KEGG Gene ID

sce:YBR145W

PubChem

852442

Alliance of Genome Resources

SGD:S000000349

Annotation

Keyword

Cytoplasm
Isopeptide bond
Metal-binding
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Ubl conjugation
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P38113	Alcohol dehydrogenase V

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
amino acid catabolic process to alcohol via Ehrlich pathway	IGI	12499363
NADH oxidation	IMP	15082781
glycolytic fermentation to ethanol	IMP	15082781

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic substance biosynthetic process [inference]

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

fermentation [inference]

glycolytic fermentation [inference]

glycolytic fermentation to ethanol

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

glycolytic fermentation to ethanol

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

glycolytic fermentation to ethanol

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process [inference]

glycolytic fermentation to ethanol

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

glycolytic fermentation to ethanol

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic substance biosynthetic process [inference]

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process [inference]

glycolytic fermentation to ethanol

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

fermentation [inference]

glycolytic fermentation [inference]

glycolytic fermentation to ethanol

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

amino acid catabolic process via Ehrlich pathway [inference]

amino acid catabolic process to alcohol via Ehrlich pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process [inference]

NADH oxidation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	HDA	14562095
cytoplasm	IBA
cytoplasm	IEA
cytoplasm	HDA	14562095

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
alcohol dehydrogenase (NAD+) activity	ISS	10974568
alcohol dehydrogenase (NAD+) activity	IBA
alcohol dehydrogenase (NAD+) activity	IEA
zinc ion binding	RCA	30358795
zinc ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dehydrogenase

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
alcohol dehydrogenase (NAD+) activity
oxidoreductase activity
zinc ion binding

Displaying **all 6** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily
Polyketide synthase, enoylreductase domain

KEGG BRITE Database

Orthology

K13953

Name

alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]

References

7608988

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
nucleus	PMID:14562095
cytoplasm	PMID:14562095

Rhea

a primary alcohol + NAD⁺

H⁺ + an aldehyde + NADH

Enzyme

PMID

ethanol + NAD⁺

acetaldehyde + H⁺ + NADH

Enzyme

1.1.1.1

PMID

a secondary alcohol + NAD⁺

H⁺ + a ketone + NADH

Enzyme

1.1.1.1

PMID

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	852442	WB:WBGene00017060
Caenorhabditis elegans	854068	WB:WBGene00017060

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Last updated: December 8, 2025