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UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Summary

Gene Symbol

ALG7

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852545

KEGG Gene ID

sce:YBR243C

PubChem

852545

Alliance of Genome Resources

SGD:S000000447

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Magnesium
Metal-binding
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P07286	GlcNAc-1-P transferase N-acetylglucosamine-1-phosphate transferase Tunicamycin resistance protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
aerobic respiration	IMP	15794922
protein glycosylation	IEA
protein N-linked glycosylation	IEA IMP	15794922
dolichol-linked oligosaccharide biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA IEA
endoplasmic reticulum membrane	IEA
intracellular membrane-bounded organelle	IEA
endoplasmic reticulum	HDA IEA	26928762
UDP-N-acetylglucosamine transferase complex	IDA	19129246

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

UDP-N-acetylglucosamine transferase complex

endoplasmic reticulum protein-containing complex [inference]

UDP-N-acetylglucosamine transferase complex

catalytic complex [inference]

UDP-N-acetylglucosamine transferase complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	IBA IEA IMP	6096695
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
dolichol-linked oligosaccharide biosynthetic process
phosphotransferase activity, for other substituted phosphate groups
protein N-linked glycosylation
transferase activity

Displaying **all 2** entries
InterPro
Glycosyl transferase, family 4
UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase

KEGG BRITE Database

Orthology

K01001

Name

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]

References

9451016

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
endoplasmic reticulum	PMID:26928762
UDP-N-acetylglucosamine transferase complex	PMID:19129246

Rhea

RHEA:13289

UDP-N-acetyl-α-D-glucosamine

UMP

Enzyme

2.7.8.15

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080562	congenital disorder of glycosylation Ij	Alliance of Genome Resources
DOID:0110676	congenital myasthenic syndrome 13	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007029
Gene Name: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	1798		HGNC:2995
Mus musculus	13478		MGI:1196396
Drosophila melanogaster	34711		FB:FBgn0032477
Caenorhabditis elegans	190436		WB:WBGene00013362
Rattus norvegicus	300668		RGD:735124
Danio rerio	566539		ZFIN:ZDB-GENE-060526-18
Kluyveromyces lactis	2894774	28985_0:00117d
Eremothecium gossypii ATCC 10895	4621744	284811_0:000c8a
Vanderwaltozyma polyspora DSM 70294	5545769	436907_0:000cad
Zygosaccharomyces rouxii	8206758	4956_0:00123d

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements