GlyCosmos Portal

Submissions

alpha-mannosidase

Summary

Gene Symbol

AMS1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852721

PubChem

852721

Alliance of Genome Resources

SGD:S000003124

Annotation

Keyword

3D-structure
Acetylation
Glycosidase
Metal-binding
Reference proteome
Vacuole
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P22855	Alpha-D-mannoside mannohydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cellular response to glucose starvation	IMP	26947009
oligosaccharide catabolic process	IBA IMP	12723970
cellular response to nitrogen starvation	IMP	26947009
mannose metabolic process	IEA
mannose catabolic process	IMP	26947009

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

mannose catabolic process

hexose catabolic process [inference]

mannose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

mannose catabolic process

hexose catabolic process [inference]

mannose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

mannose catabolic process

hexose catabolic process [inference]

mannose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

mannose catabolic process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation [inference]

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

response to starvation [inference]

cellular response to starvation [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fungal-type vacuole membrane	IBA IDA	3281936
vacuole	IEA
Cvt complex	IDA	12479808 20659891

GO Hierarchy

cellular component

protein-containing complex [inference]

Cvt complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

fungal-type vacuole membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole

Displaying **all 5** entries
GO Term	Evidence Code	PMID
alpha-mannosidase activity	IBA IDA IEA	3281936
zinc ion binding	RCA	30358795
hydrolase activity, acting on glycosyl bonds	IEA
metal ion binding	IEA
carbohydrate binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

alpha-mannosidase activity

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
fungal-type vacuole membrane	PMID:3281936
Cvt complex	PMID:12479808 PMID:20659891

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	569595	ZFIN:ZDB-GENE-101103-4
Xenopus tropicalis	100036651	Xenbase:XB-GENE-992248
Homo sapiens	4123	HGNC:6827
Mus musculus	73744	MGI:1920994
Rattus norvegicus	246136	RGD:628787