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phosphogluconate dehydrogenase (decarboxylating) GND2

Summary

Gene Symbol

GND2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853172

PubChem

853172

Alliance of Genome Resources

SGD:S000003488

Annotation

Keyword

Gluconate utilization
NADP
Oxidoreductase
Pentose shunt
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P53319

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
pentose-phosphate shunt	IEA
pentose-phosphate shunt, oxidative branch	IMP	1328471
pentose-phosphate shunt, oxidative branch	IBA
D-gluconate metabolic process	IEA
D-gluconate catabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IBA
plasma membrane	HDA	16622836

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

1

2

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Last »
GO Term	Evidence Code	PMID
phosphogluconate dehydrogenase (decarboxylating) activity	IMP	1328471
phosphogluconate dehydrogenase (decarboxylating) activity	IBA
phosphogluconate dehydrogenase (decarboxylating) activity	IEA
oxidoreductase activity	IEA
NADP binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

phosphogluconate dehydrogenase (decarboxylating) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

6-PHOSPHOGLUCONATE dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
D-gluconate catabolic process
D-gluconate metabolic process
NADP binding
oxidoreductase activity
pentose-phosphate shunt, oxidative branch
pentose-phosphate shunt
phosphogluconate dehydrogenase (decarboxylating) activity

Displaying **all 7** entries
InterPro
6-phosphogluconate dehydrogenase, C-terminal
6-phosphogluconate dehydrogenase, NADP-binding
6-phosphogluconate dehydrogenase, decarboxylating
6-phosphogluconate dehydrogenase, domain 2
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
6-phosphogluconate dehydrogenase
NAD(P)-binding domain superfamily

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
plasma membrane	PMID:16622836

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	5226	Xenbase:XB-GENE-993357
Xenopus tropicalis	31185	Xenbase:XB-GENE-993357
Xenopus tropicalis	110208	Xenbase:XB-GENE-993357
Xenopus tropicalis	177971	Xenbase:XB-GENE-993357
Xenopus tropicalis	853172	Xenbase:XB-GENE-993357
Xenopus tropicalis	856589	Xenbase:XB-GENE-993357
Xenopus tropicalis	100360180	Xenbase:XB-GENE-993357

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OrthoDB (Group)

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Acknowledgements