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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leucine rich repeat containing G protein-coupled receptor 5
Summary
- Gene Symbol
-
- LGR5
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Golgi apparatus
- Leucine-rich repeat
- Receptor
- Reference proteome
- Repeat
- Signal
- Transducer
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0A8K8C7 |
|
| O75473 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| epithelial cell proliferation involved in renal tubule morphogenesis | ||
| hair follicle development | ||
| positive regulation of canonical Wnt signaling pathway | ||
| G protein-coupled receptor signaling pathway | ||
| regulation of cell population proliferation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| plasma membrane | ||
| nucleoplasm | ||
| trans-Golgi network membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| G protein-coupled peptide receptor activity | ||
| protein-hormone receptor activity | ||
| G protein-coupled receptor activity | ||
| transmembrane signaling receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- leucine-rich repeat-containing G-protein coupled receptor 5
- Functional Category
-
- H: Coenzyme transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled peptide receptor activity |
| hormone-mediated signaling pathway |
| protein-hormone receptor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060604 | ankyloglossia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14160 | MGI:1341817 | MOUSE01525 | ||
| 34819 | FB:FBgn0003255 | |||
| 299802 | RGD:1307733 | RATNO37558 | ||
| 520189 | BOVIN28847 | |||
| 718661 | MACMU04851 | |||
| 743138 | 9598_0:0034ca | PANTR06414 | ||
| 100016120 | MONDO34420 | |||
| 100064565 | HORSE37056 | |||
| 100081690 | ORNAN05875 | |||
| 100151994 | PIGXX25830 |
