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Guidelines

MIRAGE

THO complex subunit 5

Summary

Gene Symbol

THOC5

Organism

Homo sapiens (human)

External Links

NCBI Gene

8563

PubChem

8563

Alliance of Genome Resources

HGNC:19074

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Differentiation
Isopeptide bond
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Ubl conjugation
mRNA splicing
mRNA transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13769	Functional spliceosome-associated protein 79 NF2/meningioma region protein pK1.3 Placental protein 39.2 hTREX90

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
mRNA processing	IEA
mRNA export from nucleus	IDA	17190602
mRNA export from nucleus	IMP	22144908
mRNA export from nucleus	IBA
RNA splicing	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

cell development [inference]

hemopoiesis [inference]

embryonic hemopoiesis [inference]

primitive hemopoiesis

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

embryonic hemopoiesis [inference]

primitive hemopoiesis

animal organ development [inference]

embryonic organ development [inference]

embryonic hemopoiesis [inference]

primitive hemopoiesis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

cell development [inference]

hemopoiesis [inference]

embryonic hemopoiesis [inference]

primitive hemopoiesis

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

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GO Term	Evidence Code	PMID
transcription export complex	IDA	15833825 15998806
THO complex	IDA	15998806
THO complex part of transcription export complex	IDA	15998806
THO complex part of transcription export complex	IBA
chromosome, telomeric region	IDA	24270157

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

transcription export complex

THO complex part of transcription export complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

chromosomal region [inference]

chromosome, telomeric region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mRNA binding	IBA
protein binding	IPI	19059247 19165146 22365833 23299939 26382858 26496610 28514442 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3459	breast carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pseudonaja textilis	113450875		PSETE24916
Athene cunicularia	113486163		ATHCN16007
Electrophorus electricus	113571829		ELEEL09468
Bos indicus x Bos taurus	113907336		BOBOX33458
Vombatus ursinus	114044157		VOMUR16791
Podarcis muralis	114586470		PODMU28952
Salmo trutta	115164404		SALTR60871
Salmo trutta	115200239		SALTR22932
Salarias fasciatus	115398628		SALFA07201
Gadus morhua	115553756		GADMO04212

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025