GlyCosmos Portal

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GO Term	Evidence Code	PMID
tRNA binding	IEA
RNA binding	HDA	22658674
tyrosine-tRNA ligase activity	IDA	22291016 25533949
tyrosine-tRNA ligase activity	IBA
interleukin-8 receptor binding	TAS	10102815

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity [inference]

tyrosine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA ligase activity [inference]

tyrosine-tRNA ligase activity

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

CXCR chemokine receptor binding [inference]

interleukin-8 receptor binding

cytokine receptor binding [inference]

chemokine receptor binding [inference]

CXCR chemokine receptor binding [inference]

interleukin-8 receptor binding

small molecule binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

tRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tRNA synthetase

Functional Category

J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
tRNA aminoacylation for protein translation
tyrosine-tRNA ligase activity

Displaying **all 2** entries
InterPro
Nucleic acid-binding, OB-fold
tRNA-binding domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110199	Charcot-Marie-Tooth disease dominant intermediate C	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	8565	Xenbase:XB-GENE-491608
Mus musculus	107271	Xenbase:XB-GENE-491608	MOUSE39531
Bos taurus	281581		BOVIN24947
Rattus norvegicus	313047		RATNO34539
Danio rerio	368235		DANRE15774
Pan troglodytes	469266		PANTR20554
Canis lupus familiaris	478148		CANLF06889
Macaca mulatta	709003		MACMU22617
Monodelphis domestica	100025987		MONDO21615
Pongo abelii	100173008		PONAB19900