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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine--tRNA ligase, cytoplasmic
Summary
- UniProt ID
- P54577
- Gene Symbol
-
- YARS1
- YARS
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Aminoacyl-tRNA synthetase
- Charcot-Marie-Tooth disease
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Neurodegeneration
- Nucleus
- Phosphoprotein
- Protein biosynthesis
- Reference proteome
- tRNA-binding
- Gene Ontology (GO)
| GO Term |
|---|
| apoptotic process |
| tyrosyl-tRNA aminoacylation |
| response to starvation |
| GO Term |
|---|
| nuclear body |
| cytosol |
| extracellular space |
| nucleus |
| cytoplasm |
| GO Term |
|---|
| tyrosine-tRNA ligase activity |
| interleukin-8 receptor binding |
| RNA binding |
| ATP binding |
| small molecule binding |
| tRNA binding |
Sequence
MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 444 |
|
|||
| 518 |
|
|||
| 521 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cytosolic tRNA aminoacylation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
