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RUNX family transcription factor 1
Summary
- Gene Symbol
-
- RUNX1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Chloride
- Chromosomal rearrangement
- DNA-binding
- Disease variant
- Methylation
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Repressor
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q01196 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| ossification | ||
| chondrocyte differentiation | ||
| myeloid leukocyte differentiation | ||
| regulation of transcription by RNA polymerase II |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of developmental process [inference]
negative regulation of multicellular organismal process [inference]
regulation of developmental process [inference]
regulation of cell differentiation
negative regulation of developmental process [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| transcription corepressor binding | ||
| transcription coactivator binding | ||
| DNA-binding transcription activator activity, RNA polymerase II-specific |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- runt
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| chondrocyte differentiation |
| hemopoiesis |
| neuron differentiation |
| ossification |
| regulation of cell differentiation |
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 860 | WB:WBGene00004393 | ||
| 861 | Xenbase:XB-GENE-483164 | ||
| 864 | WB:WBGene00004393 | ||
| 12393 | WB:WBGene00004393 | ||
| 12394 | MOUSE17968 | ||
| 50662 | Xenbase:XB-GENE-483164 | RATNO04350 | |
| 58126 | DANRE18572 | ||
| 487746 | CANLF12851 | ||
| 529631 | BOVIN15565 | ||
| 696749 | MACMU32002 |
