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MIRAGE
eukaryotic translation initiation factor 3 subunit F
Summary
- Gene Symbol
-
- EIF3F
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Disease variant
- Initiation factor
- Intellectual disability
- Phosphoprotein
- Reference proteome
- Thiol protease
- Ubl conjugation pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| O00303 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| formation of cytoplasmic translation initiation complex | ||
| translational initiation | ||
| translational initiation | ||
| translational initiation | ||
| proteolysis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| eukaryotic translation initiation factor 3 complex | ||
| eukaryotic translation initiation factor 3 complex | ||
| eukaryotic translation initiation factor 3 complex | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| translation initiation factor activity | ||
| translation initiation factor activity | ||
| translation initiation factor activity | ||
| translation initiation factor activity | ||
| cysteine-type deubiquitinase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Eukaryotic translation initiation factor 3
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metallopeptidase activity |
| InterPro |
|---|
| EIF3F/CSN6-like, C-terminal |
| JAB1/MPN/MOV34 metalloenzyme domain |
| MPN domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081228 | autosomal recessive intellectual developmental disorder 67 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 122199779 | PANLE13957 | ||
| 123782741 | URSAM24482 |
