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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic alpha 6 subunit
Summary
- Gene Symbol
-
- CHRNA6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15825 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synaptic transmission, cholinergic | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport | ||
| presynaptic modulation of chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| plasma membrane | ||
| neuron projection | ||
| acetylcholine-gated channel complex | ||
| dopaminergic synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1574 | alcohol use disorder | |
| DOID:3635 | congenital myasthenic syndrome | |
| DOID:809 | cocaine abuse |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11440 | MGI:106213 | MOUSE59749 | ||
| 31767 | FB:FBgn0015519 | |||
| 38545 | FB:FBgn0000038 | |||
| 40521 | FB:FBgn0266347 | |||
| 42918 | FB:FBgn0000036 | |||
| 42919 | FB:FBgn0000039 | |||
| 42920 | FB:FBgn0004118 | |||
| 81721 | RGD:69281 | RATNO10900 | ||
| 172105 | WB:WBGene00006774 | |||
| 172150 | WB:WBGene00006797 |
