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MIRAGE
Neuronal acetylcholine receptor subunit alpha-6
Summary
- UniProt ID
- Q15825
- Gene Symbol
-
- CHRNA6
- Gene ID
- 8973
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q15825
- The Human Metabolome Database
- HMDBP12053
- Re-Glyco
- Q15825
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| neuron projection |
| synapse |
| postsynaptic membrane |
| acetylcholine-gated channel complex |
| presynaptic membrane |
| dopaminergic synapse |
| GO Term |
|---|
| acetylcholine receptor activity |
| acetylcholine-gated monoatomic cation-selective channel activity |
Sequence
MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Highly calcium permeable nicotinic acetylcholine receptors | Homo sapiens |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1574 | alcohol use disorder | |
| DOID:809 | cocaine abuse |
