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Standards Ontologies Notations
Guidelines
MIRAGE
matrix metallopeptidase 20

Summary
Gene Symbol
  • MMP20
Organism
Homo sapiens (human)
NCBI Gene
9313
PubChem
9313
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Amelogenesis imperfecta
  • Autocatalytic cleavage
  • Calcium
  • Disulfide bond
  • Extracellular matrix
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
O60882
  • Enamel metalloproteinase
  • Enamelysin
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
proteolysis
extracellular matrix disassembly
protein catabolic process
extracellular matrix organization
collagen catabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
matrix metalloproteinase
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
collagen catabolic process
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding
Displaying entries 1 - 10 of 12 in total
InterPro
Hemopexin, conserved site
Hemopexin-like domain superfamily
Hemopexin-like domain
Hemopexin-like repeats
Metallopeptidase, catalytic domain superfamily
PGBD-like superfamily
Peptidase M10, metallopeptidase
Peptidase M10A, catalytic domain
Peptidase M10A, cysteine switch, zinc binding site
Peptidase M10A
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0110060 amelogenesis imperfecta hypomaturation type 2A2
Ortholog
Displaying entries 81 - 82 of 82 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
122200183 PANLE15019
123792351 URSAM11473
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025