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MIRAGE
ADAM metallopeptidase with thrombospondin type 1 motif 4
Summary
- Gene Symbol
-
- ADAMTS4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| O75173 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| skeletal system development | ||
| proteolysis | ||
| extracellular matrix disassembly | ||
| extracellular matrix organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| nuclear speck | ||
| extracellular matrix | ||
| collagen-containing extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protease binding | ||
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| protein binding | ||
| peptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 112910058 | VULVU36232 | ||
| 113883797 | BOBOX06739 | ||
| 114037842 | VOMUR25974 | ||
| 116816121 | CHEAB22338 | ||
| 117312184 | TURTR12850 | ||
| 122211643 | PANLE30641 | ||
| 123783502 | URSAM01561 |
