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potassium voltage gated channel, Shaw-related subfamily, member 4

Summary

Gene Symbol

Kcnc4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

99738

PubChem

99738

Alliance of Genome Resources

MGI:96670

Annotation

Keyword

Glycoprotein
Metal-binding
Phosphoprotein
Potassium channel
Proteomics identification
Reference proteome
Transmembrane helix
Voltage-gated channel
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A571BG98
Q8R1C0	Potassium voltage-gated channel subfamily C member 4 Voltage-gated potassium channel subunit Kv3.4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
action potential	IBA
regulation of neurotransmitter secretion	IMP	15610163
protein homooligomerization	IEA
potassium ion transmembrane transport	IBA
potassium ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

negative regulation of biological process [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of action potential [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential

regulation of action potential [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

Displaying entries **11 - 15** of 20 in total

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GO Term	Evidence Code	PMID
presynaptic membrane	IBA
neuronal cell body	ISO
axon terminus	IDA	15610163
axon terminus	IBA
calyx of Held	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

dendrite membrane

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

leading edge membrane [inference]

neuron projection membrane [inference]

dendrite membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

cell body membrane [inference]

neuronal cell body membrane

neuron projection terminus [inference]

axon terminus

calyx of Held

presynapse [inference]

axon terminus

calyx of Held

postsynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
voltage-gated potassium channel activity	ISS
voltage-gated potassium channel activity	ISO
delayed rectifier potassium channel activity	IBA
metal ion binding	IEA
voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Potassium channel

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
delayed rectifier potassium channel activity
monoatomic ion channel activity
monoatomic ion transport
potassium channel activity
protein homooligomerization
voltage-gated potassium channel activity

Displaying **all 6** entries
InterPro
BTB/POZ domain
Ion transport domain
Potassium channel tetramerisation-type BTB domain
Potassium channel, voltage dependent, Kv
SKP1/BTB/POZ domain superfamily
Voltage-dependent channel domain superfamily

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	3746	FB:FBgn0003386
Drosophila melanogaster	3747	FB:FBgn0085395
Drosophila melanogaster	3748	FB:FBgn0003386
Homo sapiens	3749	Xenbase:XB-GENE-6032635	HUMAN51222
Drosophila melanogaster	16502	FB:FBgn0085395
Drosophila melanogaster	16504	FB:FBgn0085395
Drosophila melanogaster	25327	FB:FBgn0085395
Xenopus tropicalis	33599	Xenbase:XB-GENE-6032635
Xenopus tropicalis	99738	Xenbase:XB-GENE-6032635
Drosophila melanogaster	246153	FB:FBgn0085395