G00035MO

Summary
GlyTouCan ID
G00035MO
IUPAC Condensed
GlcNAc(b1-3)GalNAc(a1-
Motifs
O-Glycan core 3
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
424.17
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
3347 30844 33470 38651 42738 43960 47102
3D Structures
GlycoShape
G00035MO
Displaying 1 entry
Archetype α β
G00036MO
G00035MO
G75113PZ
GlycoGene Database (GGDB)
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT5 UDP-Gal
G00035MO
a-OpNp
G11647UD
a-OpNp
GCNT3 UDP-GlcNAc
G00035MO
Ser/Thr
G00037MO
Ser/Thr
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 11 - 14 of 14 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GNT6 UDP-GlcNAc
G57321FI
O-glycan Synthesis
G00035MO
O-glycan Synthesis
GCNT3 UDP-GlcNAc
G00035MO
Ser/Thr
G00037MO
Ser/Thr
GCNT1 UDP-GlcNAc
G00035MO
[alpha]-pNP
G00037MO
[alpha]-pNP
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 8 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
C1GALT1 UDP-Gal
G00035MO
O-glycan Synthesis
B3GNT8 UDP-GlcNAc
G00035MO
core 3-pNp
A4GNT UDP-GlcNAc
G00035MO
pNP
B3GNT7 UDP-GlcNAc
G00035MO
core 3-pNp
B3GNT6 UDP-GlcNAc
G00035MO
[alpha]-pNP(core 3)
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R05915
R05909
Core Protein
Displaying 1 entry
UniProt ID Protein Name Reference Source
Q02817 Mucin-2
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dglc-HEX-1:5
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3d(2+1)4n
WURCS
WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2122h-1b_1-5_2*NCC/3=O]/1-2/a3-b1
Literature
Displaying entries 11 - 20 of 24 in total
PubMed ID Title First Author Publication Date Source
9892646 A β-1,3- N -acetylglucosaminyltransferase with poly- N -acetyllactosamine synthase activity is structurally related to β-1,3-galactosyltransferases Zhou D 1999 Jan 19
  • PubChem
9988682 Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4 Schwientek T 1999 Feb 19
  • PubChem
10430883 Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin Nakayama J 1999 Aug 03
  • PubChem
9792633 Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis Schwientek T 1998 Nov 06
  • PubChem
1627559 The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins Klein A 1992 Jul 7
  • GlyGen
3345750 Primary structure of neutral oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500-MHz 1H-NMR spectroscopy and quantitative sugar analysis. 2. Structure of 19 oligosaccharides having the GlcNAc beta(1----3)GalNAc-ol core (type 3) or the GlcNAc beta(1----3)[GlcNAc beta(1----6)]GalNAc-ol core (type 4) Breg J 1988 Feb 1
  • GlyGen
4008490 Oligosaccharide structures of human colonic mucin Podolsky DK 1985 Jul 15
  • GlyGen
  • PubChem
4066681 Oligosaccharide structures of isolated human colonic mucin species Podolsky DK 1985 Dec 15
  • GlyGen
  • PubChem
2580706 Structural analysis of the O-glycosidically linked core-region oligosaccharides of human meconium glycoproteins which express oncofoetal antigens Hounsell EF 1985 Apr 15
  • GlyGen
6487655 The combination of normal-phase and reverse-phase high-pressure liquid chromatography with NMR for the isolation and characterization of oligosaccharide alditols from ovarian cyst mucins Dua VK 1984 Nov 6
  • GlyGen
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificity.
  • Holgersson J
  • Löfling J
Glycobiology 2006 Jul 16484342
Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography.
  • Tachibana K
  • Nakamura S
  • Wang H
  • Iwasaki H
  • Tachibana K
  • Maebara K
  • Cheng L
  • Hirabayashi J
  • Narimatsu H
Glycobiology 2006 Jan 16177266
Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine.
  • Korekane H
  • Taguchi T
  • Sakamoto Y
  • Honke K
  • Dohmae N
  • Salminen H
  • Toivonen S
  • Helin J
  • Takio K
  • Renkonen O
  • Taniguchi N
Glycobiology 2003 May 12626393
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.
  • Uchimura K
  • El-Fasakhany FM
  • Hori M
  • Hemmerich S
  • Blink SE
  • Kansas GS
  • Kanamori A
  • Kumamoto K
  • Kannagi R
  • Muramatsu T
J Biol Chem 2002 Feb 8 11726653
Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans.
  • Iwai T
  • Inaba N
  • Naundorf A
  • Zhang Y
  • Gotoh M
  • Iwasaki H
  • Kudo T
  • Togayachi A
  • Ishizuka Y
  • Nakanishi H
  • Narimatsu H
J Biol Chem 2002 Apr 12 11821425

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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