• G00114

• 2.4.1.62
• 2.4.1.92
• 2.4.3.8

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7b:b-dgal-HEX-1:5
8s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
6:2o(4+1)7d
7:7d(2+1)8n

• Cheresh DA et al. Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J Cell Biol. 1986 Mar;102:(3):688-96. doi: 10.1083/jcb.102.3.688. PMID: 3005335.

• Kotani M et al. Immunohistochemical localization of minor gangliosides in the rat central nervous system. Glycobiology. 1994 Dec;4:(6):855-65. doi: 10.1093/glycob/4.6.855. PMID: 7734848.

• Longee DC et al. Disialoganglioside GD2 in human neuroectodermal tumor cell lines and gliomas. Acta Neuropathol. 1991;82:(1):45-54. doi: 10.1007/BF00310922. PMID: 1659106.

• Vriesendorp FJ et al. Preclinical analysis of radiolabeled anti-GD2 immunoglobulin G. Cancer. 1997 Dec 15;80:(12 Suppl):2642-9. doi: 10.1002/(sici)1097-0142(19971215)80:12+<2642::aid-cncr40>3.3.co;2-n. PMID: 9406719.

• Thurin J et al. Monoclonal antibody-defined correlations in melanoma between levels of GD2 and GD3 antigens and antibody-mediated cytotoxicity. Cancer Res. 1987 Mar 1;47:(5):1229-33. PMID: 3815333.

• Vick WW et al. Application of a panel of antiganglioside monoclonal antibodies to cytologic specimens. Acta Cytol. 1992 Sep-Oct;36:(5):697-705. PMID: 1523927.

• Kawashima I et al. Immunocytochemical analysis of gangliosides in rat primary cerebellar cultures using specific monoclonal antibodies. Brain Res. 1996 Sep 2;732:(1-2):75-86. doi: 10.1016/0006-8993(96)00493-3. PMID: 8891271.

• Mujoo K et al. Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth. Cancer Res. 1987 Feb 15;47:(4):1098-104. PMID: 3100030.

• Lode HN et al. Detection of neuroblastoma cells in CD34+ selected peripheral stem cells using a combination of tyrosine hydroxylase nested RT-PCR and anti-ganglioside GD2 immunocytochemistry. Eur J Cancer. 1997 Oct;33:(12):2024-30. doi: 10.1016/s0959-8049(97)00243-8. PMID: 9516847.

• Yamaguchi H et al. Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient. Proc Natl Acad Sci U S A. 1990 May;87:(9):3333-7. doi: 10.1073/pnas.87.9.3333. PMID: 2159145.

• Cheresh DA et al. Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells. Proc Natl Acad Sci U S A. 1984 Sep;81:(18):5767-71. doi: 10.1073/pnas.81.18.5767. PMID: 6385004.

• Ozawa H et al. Generation of one set of monoclonal antibodies specific for b-pathway ganglio-series gangliosides. Biochim Biophys Acta. 1992 Jan 24;1123:(2):184-90. doi: 10.1016/0005-2760(92)90110-h. PMID: 1371229.

• Kawashima I et al. Characterization of ganglioside expression in human melanoma cells: immunological and biochemical analysis. J Biochem. 1993 Aug;114:(2):186-93. doi: 10.1093/oxfordjournals.jbchem.a124153. PMID: 8262898.

• Cheresh DA et al. Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res. 1986 Oct;46:(10):5112-8. PMID: 3019521.

• Sen G et al. Induction of IgG antibodies by an anti-idiotype antibody mimicking disialoganglioside GD2. J Immunother. 1998 Jan;21:(1):75-83. doi: 10.1097/00002371-199801000-00010. PMID: 9456440.

• Zenita K et al. Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages. J Immunol. 1990 Jun 1;144:(11):4442-51. PMID: 2111348.

• Cahan LD et al. Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2. Proc Natl Acad Sci U S A. 1982 Dec;79:(24):7629-33. doi: 10.1073/pnas.79.24.7629. PMID: 6296843.

• Sen G et al. Preclinical evaluation in nonhuman primates of murine monoclonal anti-idiotype antibody that mimics the disialoganglioside GD2. Clin Cancer Res. 1997 Nov;3:(11):1969-76. PMID: 9815586.

• Cheung NK et al. Monoclonal antibodies to a glycolipid antigen on human neuroblastoma cells. Cancer Res. 1985 Jun;45:(6):2642-9. PMID: 2580625.

• Schulz G et al. Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res. 1984 Dec;44:(12 Pt 1):5914-20. PMID: 6498849.

• Ravindranath MH et al. Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer. Biochem Biophys Res Commun. 2004 Nov 5;324:(1):154-65. doi: 10.1016/j.bbrc.2004.09.029. PMID: 15464996.

• Yuki N et al. Pathogenesis of the neurotoxicity caused by anti-GD2 antibody therapy. J Neurol Sci. 1997 Aug;149:(2):127-30. doi: 10.1016/s0022-510x(97)05390-2. PMID: 9171318.

• Tai T et al. Different fine binding specificities of monoclonal antibodies to disialosylganglioside GD2. J Biochem. 1988 Apr;103:(4):682-7. doi: 10.1093/oxfordjournals.jbchem.a122329. PMID: 3170507.