G26238GL
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| MFNG | UDP-GlcNAc |
|
-pNP |
|
-pNP | |
| LFNG | UDP-GlcNAc |
|
[alpha]-pNp |
|
[alpha]-pNp | |
| LFNG | UDP-GlcNAc |
|
-O-EGF |
|
-O-EGF | |
| MFNG | UDP-GlcNAc |
|
-O-EGF |
|
-O-EGF |
RES 1b:a-lgal-HEX-1:5|6:d 2b:b-dglc-HEX-1:5 3s:n-acetyl LIN 1:1o(3+1)2d 2:2d(2+1)3n
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 24803430 | Fringe-mediated extension of O -linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands | Taylor P | 2014 May 06 |
|
| 20883017 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor | Hiruma-Shimizu K | 2010 Sep 30 |
|
| 10935626 | Fringe is a glycosyltransferase that modifies Notch | Moloney DJ | 2000 Jul 27 |
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025