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G99041PQ
Summary
- GlyTouCan ID
-
G99041PQ
- IUPAC Condensed
- GlcA(b1-3)Gal(b1-
- Motifs
- Galactosylceramide
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 356.1
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference |
|---|---|---|---|---|
| EXT1 | UDP-GalNAc |
G99041PQ
|
O-C2H4NHCbz mixture of EXT1 and EXT2 | |
| EXT1 | UDP-GalNAc |
G99041PQ
|
O-C2H4NHCbz | |
| EXT2 | UDP-GalNAc |
G99041PQ
|
O-C2H4NHCbz mixture of EXT1 and EXT2 | |
| EXT2 | UDP-GalNAc |
G99041PQ
|
O-C2H4NHCbz | |
| EXTL1 | UDP-GlcNAc |
G99041PQ
|
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dgal-HEX-1:5 2b:b-dglc-HEX-1:5|6:a LIN 1:1o(3+1)2d
- WURCS
- WURCS=2.0/2,2,1/[a2112h-1b_1-5][a2122A-1b_1-5]/1-2/a3-b1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 12907685 | In vitro heparan sulfate polymerization: crucial roles of core protein moieties of primer substrates in addition to the EXT1-EXT2 interaction | Kim BT | 2003 Oct 24 |
|
| 12562774 | Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis | Pedersen LC | 2003 Apr 18 |
|
| 11390981 | Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N -acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis | Kim B | 2001 Jun 05 |
|
| 11121397 | rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate | Kitagawa H | 2001 Feb 16 |
|
| 11139592 | Molecular cloning and expression of an N-acetylgalactosamine-4-O-sulfotransferase that transfers sulfate to terminal and non-terminal beta 1,4-linked N-acetylgalactosamine | Kang HG | 2001 Apr 06 |
|
| 10318803 | The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate | Kitagawa H | 1999 May 14 |
|
| 2127885 | The mechanism of initiation of chondroitin sulphate synthesis by beta-D-galactosides | Bradbeer M | 1990 Sep |
|
