fucosyltransferase 2 (H blood group)

Summary
Gene Symbol
  • FUT2
Aliases
  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2
  • SEC2
  • Se2
  • alpha (1,2) fucosyltransferase
  • alpha(1,2)FT2
  • galactoside 2-alpha-L-fucosyltransferase 2
  • secretor blood group alpha-2-fucosyltransferase
  • secretor factor
  • sej
Organism
Homo sapiens (human)
External Links
NCBI Gene
2524
GGDB ID
HGNC
4013
mRNA
map
  • 19q13.3
Protein
OMIM
KEGG Gene ID
hsa:2524
PubChem
2524
Alliance of Genome Resources
Annotation
Keyword
  • Blood group antigen
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid metabolism
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q10981
  • Alpha(1,2)FT 2
  • Fucosyltransferase 2
  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2
  • SE2
  • Secretor blood group alpha-2-fucosyltransferase
  • Secretor factor
  • Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2
  • Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2
A8K2L2
Gene Ontology (GO)
GO Hierarchy
GlycoGene Database (GGDB)
GGDB ID
gg002
Gene Symbol
  • FUT2
Reactions
Displaying all 3 entries
Donor Acceptor Product Reference
GDP-Fuc
G11042HO
G57920AK
GDP-Fuc
G00055MO
G61459JW
GDP-Fuc
G00056MO
G40696TO
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Rattus norvegicus NP_113823 NM_031635
Mus musculus NP_061364 NM_018876
Disease
Disease Ontology
Displaying entries 1 - 10 of 128 in total
DO ID Disease Name Source
DOID:1287 cardiovascular system disease
DOID:1324 lung cancer
DOID:0050589 inflammatory bowel disease
DOID:0050731 vitamin B12 deficiency
DOID:0060025 immunoglobulin alpha deficiency
DOID:0060180 colitis
DOID:0060188 jejunoileitis
DOID:0060189 ileitis
DOID:0060190 ileocolitis
DOID:0060191 gastroduodenal Crohn's disease
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP001448
Gene Name
fucosyltransferase 2 (secretor status included)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024