tankyrase

Summary
Gene Symbol
  • TNKS
Aliases
  • ARTD5
  • PARP-5a
  • PARP5A
  • TIN1
  • TINF1
  • TNKS1
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 1
  • pART5
Organism
Homo sapiens (human)
External Links
NCBI Gene
8658
HGNC
11941
PubChem
8658
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ADP-ribosylation
  • ANK repeat
  • Alternative splicing
  • Cytoskeleton
  • Glycosyltransferase
  • Golgi apparatus
  • Membrane
  • Metal-binding
  • Mitosis
  • NAD
  • Nuclear pore complex
  • Nucleotidyltransferase
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Telomere
  • Ubl conjugation
  • Wnt signaling pathway
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
H0YAW5
O95271
  • ADP-ribosyltransferase diphtheria toxin-like 5
  • Poly [ADP-ribose] polymerase 5A
  • Protein poly-ADP-ribosyltransferase tankyrase-1
  • TNKS-1
  • TRF1-interacting ankyrin-related ADP-ribose polymerase
  • Tankyrase I
  • Tankyrase-1
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000173273

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Disease
Disease Ontology
Displaying entries 1 - 10 of 137 in total
DO ID Disease Name Source
DOID:0050424 familial adenomatous polyposis
DOID:0050569 Seckel syndrome
DOID:0050789 tarsal-carpal coalition syndrome
DOID:0050902 medulloblastoma
DOID:0060254 Robinow syndrome
DOID:0060578 Noonan syndrome 1
DOID:0060580 Noonan syndrome 2
DOID:0060581 Noonan syndrome 3
DOID:0060582 Noonan syndrome 4
DOID:0060583 Noonan syndrome 5

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024