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Cyclin-dependent kinase inhibitor 1B
Summary
- UniProt ID
- O08769
- Gene Symbol
-
- Cdkn1b
- p27Kip1
- Gene ID
- 83571
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cytoplasm
- Endosome
- Nucleus
- Phosphoprotein
- Protein kinase inhibitor
- Proteomics identification
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| protein-containing complex |
| nucleoplasm |
| endosome |
| cytosol |
| Cul4A-RING E3 ubiquitin ligase complex |
| nucleus |
| GO Term |
|---|
| negative regulation of vascular associated smooth muscle cell proliferation |
| negative regulation of cardiac muscle tissue regeneration |
| regulation of G1/S transition of mitotic cell cycle |
| GO Term |
|---|
| Hsp70 protein binding |
| ubiquitin protein ligase binding |
| protein-containing complex binding |
Sequence
MSNVRVSNGSPSLERMDARQTEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGRYEWQEVERGSLPEFYYRPPRPPKSACKVPAQESLDVSGSRQAVPSIGSQANSEDRHLVDQMPDSSDSPAGLAEQCPGMRKRPAAEDSSSQNKRANRTEENVSDGSPNAGTVEQTPKKPGLRRQT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 2 |
|
|||
| 110 |
|
|||
| 197 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| p53-Dependent G1 DNA Damage Response | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050771 | pheochromocytoma | |
| DOID:0050773 | paraganglioma | |
| DOID:3125 | multiple endocrine neoplasia | |
| DOID:3829 | pituitary adenoma | |
| DOID:5223 | infertility | |
| DOID:5844 | myocardial infarction | |
| DOID:83 | cataract |
