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Solute carrier family 22 member 1

Summary

UniProt ID

O15245

Gene Symbol

SLC22A1
OCT1

Organism

Homo sapiens (human)

External Links

PubChem: O15245
The Human Metabolome Database: HMDBP02574

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Glycoprotein
Ion transport
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
neurotransmitter transport
serotonin transport
organic cation transport
monoamine transport
acetylcholine transport
dopamine transport
norepinephrine transport
epinephrine transport
establishment or maintenance of transmembrane electrochemical gradient
quaternary ammonium group transport

Displaying **all 7** entries
GO Term
basal plasma membrane
basolateral plasma membrane
apical plasma membrane
plasma membrane
membrane
presynapse
lateral plasma membrane

Displaying entries **1 - 10** of 18 in total

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GO Term
organic anion transmembrane transporter activity
dopamine:sodium symporter activity
norepinephrine:sodium symporter activity
secondary active organic cation transmembrane transporter activity
pyrimidine nucleoside transmembrane transporter activity
thiamine transmembrane transporter activity
neurotransmitter transmembrane transporter activity
putrescine transmembrane transporter activity
spermidine transmembrane transporter activity
identical protein binding

Annotation information from UniProt.

Sequence

MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKENTIYLKVQTSEPSGT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
71	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Abacavir transmembrane transport	Homo sapiens
Ciprofloxacin ADME	Homo sapiens
Na+/Cl- dependent neurotransmitter transporters	Homo sapiens
Neurotransmitter clearance	Homo sapiens
Norepinephrine Neurotransmitter Release Cycle	Homo sapiens
Organic cation transport	Homo sapiens