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SLC-mediated transport of neurotransmitters

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-442660

PubChem

R-HSA-442660

Description

The SLC6 gene family encodes proteins that mediate neurotransmitter uptake thus terminating a synaptic signal. The proteins mediate transport of GABA (gamma-aminobutyric acid), norepinephrine, dopamine, serotonin, glycine, taurine, L-proline, creatine and betaine. These transporters are mainly present in the CNS and PNS (Chen NH et al, 2004).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 18 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15244	Solute carrier family 22 member 2	OCT2 SLC22A2	view
O15245	Solute carrier family 22 member 1	OCT1 SLC22A1	view
P23975	Sodium-dependent noradrenaline transporter	NAT1 NET1 SLC6A2 SLC6A5	view
P30531	Sodium- and chloride-dependent GABA transporter 1	GABATR GABT1 GAT1 SLC6A1	view
P31645	Sodium-dependent serotonin transporter	HTT SERT SLC6A4	view
P48066	Sodium- and chloride-dependent GABA transporter 3	GABT3 GAT3 SLC6A11	view
P48067	Sodium- and chloride-dependent glycine transporter 1	SLC6A9	view
Q01959	Sodium-dependent dopamine transporter	DAT1 SLC6A3	view
Q695T7	Sodium-dependent neutral amino acid transporter B(0)AT1	B0AT1 SLC6A19	view
Q8NDX2	Vesicular glutamate transporter 3	SLC17A8 VGLUT3	view

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