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Desmoglein-3
Summary
- UniProt ID
- O35902
- Gene Symbol
-
- Dsg3
- Gene ID
- 13512
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| adherens junction |
| spot adherens junction |
| bicellular tight junction |
| desmosome |
| tight junction |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| calcium ion binding |
| protein dimerization activity |
Sequence
MTCLFPRALGSLALLMVVLLVQGELHVKPGGQHREDGTALQLAKRRYKREWVKFAKPCREREDNSRRNPIAKITSDFQKNQKITYRISGVGIDQPPFGIFVVDPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNPPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEVRTLTSSLDREQISSYHLVVSGADNDGTGLSTQCECSIKIKDVNDNFPVLRESQYSARIEENTLNAELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKVVKALDYEQVQSMQFSIAVRNKAEFHQSVISQYRVQSTPVTIQVIDVREGISFRPPSKTFTVQRGVSTNKLVGYILGTYQATDEDTGKAASSVRYVLGRNDGGLLVIDSKTAQIKFVKNIDRDSTFIVNKTISAEVLAIDENTGKTSTGTIYVEVPSFNENCPSVVLEKKDICTSSPSVTLSVRTLDRGKYTGPYTVSLEEQPLKLPVMWTITTLNATSALLQAQQQVSPGVYNVPVIVKDNQDGLCDTPESLTLTVCQCDDRSMCRAPIPSREPNTYGESSWRLGPAAIGLILLGLLMLLLAPLLLLTCDCGSGPIGGAATGGFIPVPDGSEGTIHQWGIEGAQPEDKEITNICVPPVTTNGADFMESSEVCTNTYAGGTMVEGASGMEMITKLGGATGATAALGPCSLGYSGTMRTRHSTGGTLKDYAAPVNMTFLGSYFSQKSLAYAEEEDEREVNDCLLIYDDEGEDAAPHSPTLSSCSIFGDDLDDNFLDSLGPKFKKLAEICLGIDDEAKQAKPGPKDSGSGADTCARSMEVPQSGSNRYQTLPGSLEVTQTGSKICHTLSGNQETSVMSTSGSVHPAVAIPDPLQLGNYLLTETYSTSGSFAQPTTVTFDPHVTQNVTVTERVICPLPSASSSIVAPTELRGSYNMLYTKETCSHL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Apoptotic cleavage of cell adhesion proteins | Mus musculus |
| Formation of the cornified envelope | Mus musculus |
| Keratinization | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060851 | pemphigus vulgaris |
