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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Frizzled-6
Summary
- UniProt ID
- O60353
- Gene Symbol
-
- FZD6
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- O60353
- PubChem
- O60353
- The Human Metabolome Database
- HMDBP07702
- The O-GlcNAc Database
- O60353
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytoplasmic vesicle
- Developmental protein
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| cell surface |
| apical plasma membrane |
| apicolateral plasma membrane |
| plasma membrane |
| cytoplasmic vesicle membrane |
| GO Term |
|---|
| Wnt-protein binding |
| G protein-coupled receptor activity |
| ubiquitin protein ligase binding |
| Wnt receptor activity |
Sequence
MEMFTFLLTCIFLPLLRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFWCPRHLKTSGGQGYKFLGIDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATANHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKGSTSLLVHPVSGVRKEQGGGCHSDT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 38 | N-linked (GlcNAc...) asparagine | |||
| 126 |
|
|||
| 129 |
|
|||
| 136 |
|
|||
| 141 |
|
|||
| 150 |
|
|||
| 352 | N-linked (GlcNAc...) asparagine |
|
||
| 585 |
|
|||
| 587 |
|
G12793SR
G99679NM
G27947YN
G52527GH
G57321FI
G43417UB
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ca2+ pathway | Homo sapiens |
| Class B/2 (Secretin family receptors) | Homo sapiens |
| PCP/CE pathway | Homo sapiens |
| Regulation of FZD by ubiquitination | Homo sapiens |
| Signaling by RNF43 mutants | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
