Class B/2 (Secretin family receptors)

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-373080
PubChem
R-HSA-373080
Description
  • This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying entries 1 - 10 of 43 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O00144 Frizzled-9
  • FZD3
  • FZD9
view
O00744 Protein Wnt-10b
  • WNT10B
  • WNT12
view
O00755 Protein Wnt-7a
  • WNT7A
view
O14904 Protein Wnt-9a
  • WNT14
  • WNT9A
view
O14905 Protein Wnt-9b
  • UNQ6973/PRO21956
  • WNT14B
  • WNT15
  • WNT9B
view
O60353 Frizzled-6
  • FZD6
view
O75084 Frizzled-7
  • FZD7
view
O96014 Protein Wnt-11
  • WNT11
view
P04628 Proto-oncogene Wnt-1
  • INT1
  • WNT1
view
P08174 Complement decay-accelerating factor
  • CD55
  • CR
  • DAF
view

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026