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Proto-oncogene Wnt-1
Summary
- UniProt ID
- P04628
- Gene Symbol
-
- INT1
- WNT1
- Gene ID
- 7471
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Developmental protein
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Lipoprotein
- Osteogenesis imperfecta
- Osteoporosis
- Proto-oncogene
- Reference proteome
- Signal
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| cytoplasm |
| plasma membrane |
| endoplasmic reticulum lumen |
| Golgi lumen |
| cell surface |
| endocytic vesicle membrane |
| extracellular exosome |
| GO Term |
|---|
| morphogen activity |
| cytokine activity |
| protein domain specific binding |
| frizzled binding |
| receptor ligand activity |
Sequence
MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Class B/2 (Secretin family receptors) | Homo sapiens |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | Homo sapiens |
| PCP/CE pathway | Homo sapiens |
| TCF dependent signaling in response to WNT | Homo sapiens |
| Transcriptional regulation of white adipocyte differentiation | Homo sapiens |
| WNT ligand biogenesis and trafficking | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110347 | osteogenesis imperfecta type 15 |
