Serine/threonine-protein kinase PAK 3

Summary
UniProt ID
O75914
Gene Symbol
  • PAK3
  • OPHN3
Organism
Homo sapiens (human)
GlyGen
O75914
PubChem
O75914
The Human Metabolome Database
HMDBP01400
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Allosteric enzyme
  • Alternative splicing
  • Cytoplasm
  • Developmental protein
  • Disease variant
  • Intellectual disability
  • Magnesium
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • SH3-binding
  • Serine/threonine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
22
121
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 13 in total
Pathway Name Organism
Activation of RAC1 Homo sapiens
CD209 (DC-SIGN) signaling Homo sapiens
CD28 dependent Vav1 pathway Homo sapiens
CDC42 GTPase cycle Homo sapiens
Ephrin signaling Homo sapiens
Generation of second messenger molecules Homo sapiens
MAPK6/MAPK4 signaling Homo sapiens
RAC1 GTPase cycle Homo sapiens
RHO GTPases activate PAKs Homo sapiens
RHOJ GTPase cycle Homo sapiens

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024