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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Erlin-2
Summary
- UniProt ID
- O94905
- Gene Symbol
-
- ERLIN2
- C8orf2
- SPFH2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cholesterol metabolism
- Direct protein sequencing
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Hereditary spastic paraplegia
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| protein-containing complex |
| membrane raft |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| cytosol |
| GO Term |
|---|
| cholesterol binding |
| ubiquitin protein ligase binding |
Sequence
MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 106 | N-linked (GlcNAc...) asparagine | |||
| 108 |
|
|||
| 315 |
|
|||
| 323 |
|
|||
| 326 |
|
|||
| 334 |
|
|||
| 336 |
|
G83460ZZ
G01650EU
G23294PN
G70101JE
G80333GO
G64527OM
G62894KT
G05724UK
G39188ZX
G25637MV
G06110VR
G49108TO
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC-family proteins mediated transport | Homo sapiens |
| Defective CFTR causes cystic fibrosis | Homo sapiens |
| Signaling by FGFR1 in disease | Homo sapiens |
| Signaling by plasma membrane FGFR1 fusions | Homo sapiens |
Human Protein Atlas