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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dickkopf-related protein 1
Summary
- UniProt ID
- O94907
- Gene Symbol
-
- DKK1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011257
- GlyGen
- O94907
- PubChem
- O94907
Annotation
- Keyword
-
- 3D-structure
- Developmental protein
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of Wnt-Frizzled-LRP5/6 complex assembly |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| early endosome membrane |
| GO Term |
|---|
| low-density lipoprotein particle receptor binding |
| growth factor activity |
| receptor antagonist activity |
| co-receptor binding |
Sequence
MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 44 |
|
|||
| 61 | O-linked (GalNAc...) serine | |||
| 68 |
|
|
||
| 74 |
|
|||
| 76 |
|
|||
| 99 |
|
|||
| 131 |
|
|
||
| 148 |
|
|||
| 153 |
|
|||
| 155 |
|
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | Homo sapiens |
| Signaling by LRP5 mutants | Homo sapiens |
| TCF dependent signaling in response to WNT | Homo sapiens |
