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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cholesterol 25-hydroxylase
Summary
- UniProt ID
- O95992
- Gene Symbol
-
- CH25H
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O95992
- SwissLipids
- The Human Metabolome Database
- HMDBP03049
Annotation
- Keyword
-
- Endoplasmic reticulum
- Glycoprotein
- Iron
- Metal-binding
- Monooxygenase
- Reference proteome
- Sterol biosynthesis
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| steroid hydroxylase activity |
| C-4 methylsterol oxidase activity |
| cholesterol 25-hydroxylase activity |
| iron ion binding |
Sequence
MSCHNCSDPQVLCSSGQLFLQPLWDHLRSWEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVPALRRYKIHPDFSPSAQQLLPCLGQTLYQHVMFVFPVTLLHWARSPALLPHEAPELLLLLHHILFCLLLFDMEFFVWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDMMNVTLLGCHPLTTLTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWDKILGTLRTASVPAR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of bile acids and bile salts | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:0060215 | Balo concentric sclerosis | |
| DOID:0060478 | Zika fever | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0110035 | Alzheimer's disease 2 | |
| DOID:0110037 | Alzheimer's disease 5 | |
| DOID:0110038 | Alzheimer's disease 6 | |
| DOID:0110039 | Alzheimer's disease 7 |
