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MIRAGE
Ceruloplasmin

Summary
UniProt ID
P00450
Gene Symbol
  • CP
Gene ID
1356
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011270
GlyConnect
GlyGen
P00450
PubChem
P00450
The Human Metabolome Database
HMDBP00472
RaftProt
P00450
Re-Glyco
P00450
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 7 entries
GO Term
extracellular region
extracellular space
plasma membrane
endoplasmic reticulum lumen
lysosomal membrane
extracellular exosome
blood microparticle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVEPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 16 in total
Position Description PubMed ID GlyTouCan ID Source
129
138 N-linked (GlcNAc...) (complex) asparagine
358 N-linked (GlcNAc...) (complex) asparagine
360
397 N-linked (GlcNAc...) (complex) asparagine
485
489
492
505
507
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Defective CP causes aceruloplasminemia (ACERULOP) Homo sapiens
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) Homo sapiens
Iron uptake and transport Homo sapiens
Metal ion SLC transporters Homo sapiens
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0050711 aceruloplasminemia
DOID:12119 hemosiderosis
DOID:1826 epilepsy
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025