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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Coagulation factor IX
Summary
- UniProt ID
- P00740
- Gene Symbol
-
- F9
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P00740
- PubChem
- P00740
- The Human Metabolome Database
- HMDBP01730
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hemophilia
- Hydroxylation
- Magnesium
- Metal-binding
- Pharmaceutical
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sulfation
- Thrombophilia
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| blood coagulation |
| zymogen activation |
| GO Term |
|---|
| endoplasmic reticulum lumen |
| Golgi lumen |
| extracellular exosome |
| extracellular region |
| extracellular space |
| plasma membrane |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| metal ion binding |
| endopeptidase activity |
Sequence
MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G28847IN
G38277AO
G12743GW
G87108ET
G10008NR
G69834CE
G86904UH
G66088HZ
G79318PG
G17827EU
G39595FH
G92975MH
G12793SR
G32551IQ
G15016TE
G15169WU
G74815GQ
G47518TP
G98725UL
G31639NG
G52527GH
G48414YA
G58489ZK
G70649KP
G10651WD
G50236GJ
G70593HA
G24693UW
G45127HA
G31189KC
G38979OV
G96881BQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Homo sapiens |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Homo sapiens |
