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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Renin
Summary
- UniProt ID
- P00797
- Gene Symbol
-
- REN
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P00797
- PubChem
- P00797
- The Human Metabolome Database
- HMDBP02624
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Aspartyl protease
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Membrane
- Reference proteome
- Secreted
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| kidney development |
| mesonephros development |
| proteolysis |
| regulation of blood pressure |
| male gonad development |
| cell maturation |
| hormone-mediated signaling pathway |
| juxtaglomerular apparatus development |
| response to cAMP |
| angiotensin maturation |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| apical part of cell |
| GO Term |
|---|
| aspartic-type endopeptidase activity |
| insulin-like growth factor receptor binding |
| signaling receptor binding |
| peptidase activity |
Sequence
MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 71 | N-linked (GlcNAc...) asparagine |
|
||
| 141 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G12932QT
G63889NK
G90093AU
G18938DW
G47012YE
G45359RY
G72797UR
G86357DX
G20425TQ
G29857RC
G79809MM
G23863VK
G78059CC
G64527OM
G67381VP
G23869AA
G36191CD
G50045TK
G14889BN
G16828VN
G72735IY
G04689DA
G05724UK
G93180LE
G15956KF
G39188ZX
G06110VR
G55220VL
G74724QE
G82348BZ
G14669DU
G22768VO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Metabolism of Angiotensinogen to Angiotensins | Homo sapiens |
