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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transforming growth factor beta-1 proprotein
Summary
- UniProt ID
- P01137
- Gene Symbol
-
- TGFB1
- TGFB
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011299
- GlyConnect
- GlyGen
- P01137
- PubChem
- P01137
- The Human Metabolome Database
- HMDBP14566
- RaftProt
- P01137
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi lumen |
| neuronal cell body |
| collagen-containing extracellular matrix |
| platelet alpha granule lumen |
| blood microparticle |
| cell surface |
| extracellular region |
| extracellular space |
| nucleus |
| cytoplasm |
Sequence
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 82 | N-linked (GlcNAc...) asparagine | |||
| 136 | N-linked (GlcNAc...) asparagine | |||
| 176 | N-linked (GlcNAc...) asparagine |
G27058EU
G25079LO
G80920RR
G01485JJ
G14260UH
G62765YT
G31852PQ
G28622IK
G41247ZX
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | Homo sapiens |
| Syndecan interactions | Homo sapiens |
| TGF-beta receptor signaling activates SMADs | Homo sapiens |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Homo sapiens |
| TGFBR1 KD Mutants in Cancer | Homo sapiens |
| TGFBR1 LBD Mutants in Cancer | Homo sapiens |
| TGFBR2 Kinase Domain Mutants in Cancer | Homo sapiens |
| TGFBR2 MSI Frameshift Mutants in Cancer | Homo sapiens |
| TGFBR3 regulates TGF-beta signaling | Homo sapiens |
| Transcriptional regulation of white adipocyte differentiation | Homo sapiens |
