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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Beta-nerve growth factor
Summary
- UniProt ID
- P01138
- Gene Symbol
-
- NGF
- NGFB
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P01138
- PubChem
- P01138
- The Human Metabolome Database
- HMDBP02581
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Growth factor
- Lipid-binding
- Metalloprotease inhibitor
- Neurodegeneration
- Neuropathy
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| axon |
| dendrite |
| endosome lumen |
| extracellular region |
| cytosol |
| Golgi lumen |
| synaptic vesicle |
| GO Term |
|---|
| nerve growth factor receptor binding |
| growth factor activity |
| metalloendopeptidase inhibitor activity |
| lipid binding |
Sequence
MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI3K/AKT activation | Homo sapiens |
| PLC-gamma1 signalling | Homo sapiens |
| Retrograde neurotrophin signalling | Homo sapiens |
| Signalling to RAS | Homo sapiens |
| Signalling to STAT3 | Homo sapiens |
| Signalling to p38 via RIT and RIN | Homo sapiens |
| TRKA activation by NGF | Homo sapiens |
| p75NTR negatively regulates cell cycle via SC1 | Homo sapiens |
| p75NTR recruits signalling complexes | Homo sapiens |
