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MIRAGE
Thyrotropin subunit beta

Summary
UniProt ID
P01222
Gene Symbol
  • TSHB
Gene ID
7252
Organism
Homo sapiens (human)
GlyGen
P01222
PubChem
P01222
Re-Glyco
P01222
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Congenital hypothyroidism
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hormone
  • Pharmaceutical
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 3 entries
GO Term
extracellular region
extracellular space
cytoplasm
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
hormone activity
Annotation information from UniProt.
Sequence
MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
43
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
G alpha (s) signalling events Homo sapiens
Glycoprotein hormones Homo sapiens
Hormone ligand-binding receptors Homo sapiens
Thyroxine biosynthesis Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0070123 congenital nongoitrous hypothyroidism 4
DOID:1459 hypothyroidism
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025