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Glycoprotein hormones

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-209822

PubChem

R-HSA-209822

Description

More complex protein hormones have carbohydrate side chains and are called glycoprotein hormones. Hormones in this class are Follicle-stimulating hormone (FSH; follitropin), Luteinizing hormone (LH), Thyroid-stimulating hormone (TSH; thyrotropin) and human chorionic gonadotropin (hCG). The alpha subunit of glycoprotein hormones is a 92 aa peptide and serves as the alpha subunit for FSH, LH, hCG and TSH (Fiddes JC and Goodman HM, 1981). The beta subunits for these hormones are unique and confer biological specificity to them. These two subunits combine via disulphide bonding to produce the mature glycoprotein hormone dimer.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 10** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P01215	Glycoprotein hormones alpha chain	CGA FSHA GPA1 hCG_33165	view
P01222	Thyrotropin subunit beta	TSHB	view
P01225	Follitropin subunit beta	FSHB	view
P01229	Lutropin subunit beta	LHB	view
P05111	Inhibin alpha chain	INHA	view
P08476	Inhibin beta A chain	INHBA	view
P09529	Inhibin beta B chain	INHBB	view
P0DN86	Choriogonadotropin subunit beta 3	CGB CGB3 CGB3; CGB5; CGB8 CGB4	view
P55103	Inhibin beta C chain	INHBC	view
P58166	Inhibin beta E chain	INHBE	view

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