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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tumor necrosis factor
Summary
- UniProt ID
- P01375
- Gene Symbol
-
- TNF
- TNFA
- TNFSF2
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P01375
- PubChem
- P01375
- The Human Metabolome Database
- HMDBP02070
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Myristate
- Phosphoprotein
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| external side of plasma membrane |
| cell surface |
| recycling endosome |
| extracellular space |
| plasma membrane |
| neuronal cell body |
| membrane raft |
| phagocytic cup |
Sequence
MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Glycosylation Sites
G48818KL
G56682BC
G74722FL
G00031MO
G29931IJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Regulation of TNFR1 signaling | Homo sapiens |
| TNF signaling | Homo sapiens |
| TNFR1-induced NF-kappa-B signaling pathway | Homo sapiens |
| TNFR1-induced proapoptotic signaling | Homo sapiens |
| TNFR1-mediated ceramide production | Homo sapiens |
| TNFR2 non-canonical NF-kB pathway | Homo sapiens |
| Transcriptional regulation of white adipocyte differentiation | Homo sapiens |
