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MIRAGE
Fibrinogen alpha chain
Summary
- UniProt ID
- P02671
- Gene Symbol
-
- FGA
- Gene ID
- 2243
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011303
- GlyConnect
- GlyGen
- P02671
- PubChem
- P02671
- The Human Metabolome Database
- HMDBP13512
- RaftProt
- P02671
- Re-Glyco
- P02671
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Amyloid
- Amyloidosis
- Blood coagulation
- Calcium
- Coiled coil
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Innate immunity
- Isopeptide bond
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular vesicle |
| extracellular region |
| fibrinogen complex |
| extracellular space |
| plasma membrane |
| collagen-containing extracellular matrix |
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
| external side of plasma membrane |
| cell surface |
Sequence
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ
Glycosylation Sites
G57321FI
G73004SD
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Paradoxical activation of RAF signaling by kinase inactive BRAF | Homo sapiens |
| Platelet degranulation | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Regulation of TLR by endogenous ligand | Homo sapiens |
| Signaling by BRAF and RAF1 fusions | Homo sapiens |
| Signaling by RAF1 mutants | Homo sapiens |
| Signaling by high-kinase activity BRAF mutants | Homo sapiens |
| Signaling by moderate kinase activity BRAF mutants | Homo sapiens |
| Signaling downstream of RAS mutants | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050636 | familial visceral amyloidosis | |
| DOID:0112313 | brain small vessel disease | |
| DOID:2236 | congenital afibrinogenemia | |
| DOID:2452 | thrombophilia |
